What is Gabapentin?
Gabapentin is a medical drug developed to treat epilepsy. At present it is widely used as a medication to treat pain, particularly neuropathic pain and to treat severe depression disorder. Gabapentin is also sold under trade names such as Neuronthin, Gralise, Fanatrex and Gabarone. Pfizer initially marketed this drug to the public.
This drug was initially manufactured to imitate the chemical structure and function of the neuro-transmitter gamma-aminobutyric acid, however it is believed not to act on the same point. A study shows that Gabapentin arrests the configuration of the new synapses. It was noted to combine with a voltage-dependent calcium channel in the central nervous system.
In 2002 it was also proven to treat patients with postherpetic neuralgia, other painful neuropathies and nerve-related pain. Gabapentin is also used as an oral treatment for the luxurious Prometa treatment for methamphetamine, alcohol and cocaine addiction. Together with another drug called flumazenil, patients have reported to having lessened yearning for methamphetamine use. Infusion of Gabapentin and flumazenil use is an approved method of treatment. However physicians are also not forbidden to prescribe the drug outside of the Prometa treatment use. It is also noted to calm patients experiencing dependency in ipioid analgesics, such as heroin, oxycodone and morphine. It is also noted to greatly decrease the effects of benzodiazepine withdrawal.
Although in some case of Gabapentin high due to abusing, some of the noted positive uses of Gabapentin are to treat several types of neuralgia, migraine headaches, neuropathic pain and nystagmus which is an involuntary movement of the eye. Treatment for this condition with the use of Gabapentin is considered as off-label. It is also considered to be effective in patients with post-operative chronic pain. This usually happens with patients who may have severed their nerves in traumatic accidents. Some this case, the nerves reconnect incorrectly that is why it causes pain. Patients with menopause who are being treated with anti-androgenic composite have also been treated with Gabapentin to decrease the frequency of hot flushes. This drug can also promote sleeping and decrease awakening at night. Gabapentin is also prescribed among patients with restless legs syndrome, a neurological disorder characterized by an irresistible desire to move one’s body to stop uncomfortable or strange sensations. It is also effective in the treatment of Akathisia which is a condition characterized by unpleasant sensations of inner restlessness that is apparent with an inability to sit still or remain motionless. This is usually a side effect upon intake of medications such as the antipsychotic drugs.